ohai.social

John Vaccaro (johniac)SciTech Chronicles. . . . . . . . . . . . . . . . . . . . .Jan 24, 2025<a href="https://bit.ly/stc012425" rel="nofollow noopener" translate="no" target="_blank">https://bit.ly/stc012425</a><a href="https://mastodon.social/tags/Buses" class="mention hashtag" rel="nofollow noopener" target="_blank">#Buses</a> <a href="https://mastodon.social/tags/autonomous" class="mention hashtag" rel="nofollow noopener" target="_blank">#autonomous</a> <a href="https://mastodon.social/tags/Imagry" class="mention hashtag" rel="nofollow noopener" target="_blank">#Imagry</a> <a href="https://mastodon.social/tags/Level" class="mention hashtag" rel="nofollow noopener" target="_blank">#Level</a>-4 <a href="https://mastodon.social/tags/self" class="mention hashtag" rel="nofollow noopener" target="_blank">#self</a>-generated <a href="https://mastodon.social/tags/map" class="mention hashtag" rel="nofollow noopener" target="_blank">#map</a> <a href="https://mastodon.social/tags/mitochondria" class="mention hashtag" rel="nofollow noopener" target="_blank">#mitochondria</a> <a href="https://mastodon.social/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a> <a href="https://mastodon.social/tags/immunotherapy" class="mention hashtag" rel="nofollow noopener" target="_blank">#immunotherapy</a> <a href="https://mastodon.social/tags/mtDNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#mtDNA</a> <a href="https://mastodon.social/tags/senescence" class="mention hashtag" rel="nofollow noopener" target="_blank">#senescence</a> <a href="https://mastodon.social/tags/open" class="mention hashtag" rel="nofollow noopener" target="_blank">#open</a>-source <a href="https://mastodon.social/tags/Cost" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cost</a> <a href="https://mastodon.social/tags/Security" class="mention hashtag" rel="nofollow noopener" target="_blank">#Security</a> <a href="https://mastodon.social/tags/Documentation" class="mention hashtag" rel="nofollow noopener" target="_blank">#Documentation</a> <a href="https://mastodon.social/tags/Customizability" class="mention hashtag" rel="nofollow noopener" target="_blank">#Customizability</a> <a href="https://mastodon.social/tags/Sustainability" class="mention hashtag" rel="nofollow noopener" target="_blank">#Sustainability</a> <a href="https://mastodon.social/tags/LLM" class="mention hashtag" rel="nofollow noopener" target="_blank">#LLM</a> <a href="https://mastodon.social/tags/Clone" class="mention hashtag" rel="nofollow noopener" target="_blank">#Clone</a> <a href="https://mastodon.social/tags/Fudan" class="mention hashtag" rel="nofollow noopener" target="_blank">#Fudan</a> <a href="https://mastodon.social/tags/Meta" class="mention hashtag" rel="nofollow noopener" target="_blank">#Meta</a> <a href="https://mastodon.social/tags/Alibaba" class="mention hashtag" rel="nofollow noopener" target="_blank">#Alibaba</a> <a href="https://mastodon.social/tags/Frontier" class="mention hashtag" rel="nofollow noopener" target="_blank">#Frontier</a> <a href="https://mastodon.social/tags/AI" class="mention hashtag" rel="nofollow noopener" target="_blank">#AI</a> <a href="https://mastodon.social/tags/Bees" class="mention hashtag" rel="nofollow noopener" target="_blank">#Bees</a> <a href="https://mastodon.social/tags/Hive" class="mention hashtag" rel="nofollow noopener" target="_blank">#Hive</a> <a href="https://mastodon.social/tags/AprilTags" class="mention hashtag" rel="nofollow noopener" target="_blank">#AprilTags</a> <a href="https://mastodon.social/tags/Pollen" class="mention hashtag" rel="nofollow noopener" target="_blank">#Pollen</a> <a href="https://mastodon.social/tags/foraging" class="mention hashtag" rel="nofollow noopener" target="_blank">#foraging</a>

Angstrom MineralsWhen it comes to boosting your <a href="https://mastodon.social/tags/immunesystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#immunesystem</a>, pumping up your intake of <a href="https://mastodon.social/tags/fruitsandveggies" class="mention hashtag" rel="nofollow noopener" target="_blank">#fruitsandveggies</a> is an important and relatively easy step. Likely, <a href="https://mastodon.social/tags/VitaminC" class="mention hashtag" rel="nofollow noopener" target="_blank">#VitaminC</a> or ascorbic acid immediately comes to mind, and there’s a good reason for that. A recent study shows <a href="https://mastodon.social/tags/ascorbicacid" class="mention hashtag" rel="nofollow noopener" target="_blank">#ascorbicacid</a> in the vitamin enhances natural killer cells or NK cells in people who recently underwent <a href="https://mastodon.social/tags/chemotherapy" class="mention hashtag" rel="nofollow noopener" target="_blank">#chemotherapy</a>. These <a href="https://mastodon.social/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a> induce <a href="https://mastodon.social/tags/apoptosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#apoptosis</a>, the death of cancer cells. <a href="https://mastodon.social/tags/angstromminerals" class="mention hashtag" rel="nofollow noopener" target="_blank">#angstromminerals</a> <a href="https://mastodon.social/tags/healthyfood" class="mention hashtag" rel="nofollow noopener" target="_blank">#healthyfood</a>

ErinQuestion to anyone familar with <a href="https://mstdn.social/tags/TransHealthcare" class="mention hashtag" rel="nofollow noopener" target="_blank">#TransHealthcare</a> <a href="https://mstdn.social/tags/Hematology" class="mention hashtag" rel="nofollow noopener" target="_blank">#Hematology</a> Is there a relationship between elevated <a href="https://mstdn.social/tags/WBC" class="mention hashtag" rel="nofollow noopener" target="_blank">#WBC</a> (<a href="https://mstdn.social/tags/neutrophils" class="mention hashtag" rel="nofollow noopener" target="_blank">#neutrophils</a>, <a href="https://mstdn.social/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a>, <a href="https://mstdn.social/tags/monocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#monocytes</a>) & <a href="https://mstdn.social/tags/Platelets" class="mention hashtag" rel="nofollow noopener" target="_blank">#Platelets</a>, decreased <a href="https://mstdn.social/tags/RBC" class="mention hashtag" rel="nofollow noopener" target="_blank">#RBC</a>, <a href="https://mstdn.social/tags/Hemocrit" class="mention hashtag" rel="nofollow noopener" target="_blank">#Hemocrit</a>, <a href="https://mstdn.social/tags/Anemia" class="mention hashtag" rel="nofollow noopener" target="_blank">#Anemia</a>, <a href="https://mstdn.social/tags/Hgb" class="mention hashtag" rel="nofollow noopener" target="_blank">#Hgb</a>, <a href="https://mstdn.social/tags/mpv" class="mention hashtag" rel="nofollow noopener" target="_blank">#mpv</a> and <a href="https://mstdn.social/tags/HRT" class="mention hashtag" rel="nofollow noopener" target="_blank">#HRT</a> for male to female <a href="https://mstdn.social/tags/transgender" class="mention hashtag" rel="nofollow noopener" target="_blank">#transgender</a> individuals with no other evidence of blood disease, infection or <a href="https://mstdn.social/tags/cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#cancer</a>? <a href="https://mstdn.social/tags/CTScans" class="mention hashtag" rel="nofollow noopener" target="_blank">#CTScans</a> are clean, <a href="https://mstdn.social/tags/BoneMarrowBiopsy" class="mention hashtag" rel="nofollow noopener" target="_blank">#BoneMarrowBiopsy</a> clean. Doc wants to repeat however.

Chuck Darwin“It’s difficult to think of a disease, injury or injection that doesn’t involve some kind of <a href="https://c.im/tags/immune" class="mention hashtag" rel="nofollow noopener" target="_blank">#immune</a> <a href="https://c.im/tags/response" class="mention hashtag" rel="nofollow noopener" target="_blank">#response</a>, and our finding really changes the way we could control this response,” said Professor Adrian Liston from the University’s Department of Pathology and the study’s corresponding author. “We’ve uncovered new rules of the immune system. This ‘unified healer army’ can do everything – repair injured muscle, make your fat cells respond better to insulin, regrow hair follicles. To think that we could use it in such an enormous range of diseases is fantastic: it’s got the potential to be used for almost everything.”Lymphoid organs are integral parts of the immune system, responsible for producing <a href="https://c.im/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a>, a type of white blood cell that includes T cells. T cells begin life in the bone marrow and then move to the thymus, an organ in the upper mid-chest, where they mature into specialized subsets, including <a href="https://c.im/tags/Tregs" class="mention hashtag" rel="nofollow noopener" target="_blank">#Tregs</a>. Once fully matured, T cells are exported to peripheral lymphatic tissues and organs like the spleen, tonsils, and lymph nodes (some move to the bloodstream). It was thought that’s where Tregs stayed, on ‘standby’ until called upon by the immune system.To test this, the researchers analyzed the Tregs present in 48 different tissues in mice, including lymphoid and non-lymphoid tissues and tissues associated with the gut. They found them in all tissue types, suggesting that Tregs weren’t specialized cell populations confined to lymphoid tissues but moved around the body, executing repair functions in areas that need it.“Now that we know these regulatory T cells are present everywhere in the body, in principle ⭐️we can start to make immune suppression and tissue regeneration treatments that are targeted against a single organ⭐️ – a vast improvement on current treatments that are like hitting the body with a sledgehammer,” Liston said <a href="https://newatlas.com/medical/regulatory-t-cells-discovery/" rel="nofollow noopener" translate="no" target="_blank">https://newatlas.com/medical/regulatory-t-cells-discovery/</a>

halama_immuno<a href="https://mstdn.science/tags/Immunology" class="mention hashtag" rel="nofollow noopener" target="_blank">#Immunology</a> in action: tumor infiltrating <a href="https://mstdn.science/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a> and microsatellite instability as factors in <a href="https://mstdn.science/tags/colorectal" class="mention hashtag" rel="nofollow noopener" target="_blank">#colorectal</a> <a href="https://mstdn.science/tags/cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#cancer</a> systematically evaluated by my brillant colleagues. Impact for clinical care: enormous. <a href="https://mstdn.science/tags/CRC" class="mention hashtag" rel="nofollow noopener" target="_blank">#CRC</a> <a href="https://mstdn.science/tags/CRCAwareness" class="mention hashtag" rel="nofollow noopener" target="_blank">#CRCAwareness</a> <a href="https://mstdn.science/tags/oncology" class="mention hashtag" rel="nofollow noopener" target="_blank">#oncology</a> <a href="https://med-mastodon.com/@luckytran" class="u-url mention" rel="nofollow noopener" target="_blank">@luckytran</a> <a href="https://qoto.org/@cyrilpedia" class="u-url mention" rel="nofollow noopener" target="_blank">@cyrilpedia</a> <a href="https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00091-8/fulltext" rel="nofollow noopener" translate="no" target="_blank">https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00091-8/fulltext</a>

Giuseppe Michieli-- A lower frequency of circulating B <a href="https://mstdn.science/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a> by mass cytometry (CyTOF) was observed in the multidomain <a href="https://mstdn.science/tags/deficit" class="mention hashtag" rel="nofollow noopener" target="_blank">#deficit</a> cluster. Circulating <a href="https://mstdn.science/tags/fibroblast" class="mention hashtag" rel="nofollow noopener" target="_blank">#fibroblast</a> growth factor 21 (FGF21) was significantly elevated in the <a href="https://mstdn.science/tags/mental" class="mention hashtag" rel="nofollow noopener" target="_blank">#mental</a>/cognitive predominant and the multidomain clusters. Future efforts to link <a href="https://mstdn.science/tags/PASC" class="mention hashtag" rel="nofollow noopener" target="_blank">#PASC</a> to acute anti-viral host responses may help to better target treatment and prevention of PASC.

katch wreck"Administration of MTA-depleting enzymes reverses this immunosuppressive effect, increasing <a href="https://mastodon.social/tags/tumor" class="mention hashtag" rel="nofollow noopener" target="_blank">#tumor</a>-infiltrating <a href="https://mastodon.social/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a> and drastically impairing tumor growth and importantly, synergizes well with immune checkpoint inhibitor (ICI) therapy. As several studies have shown ICI resistance in 9p21/MTAP null/low patients, we propose that MTA degrading <a href="https://mastodon.social/tags/therapeutics" class="mention hashtag" rel="nofollow noopener" target="_blank">#therapeutics</a> may have substantial therapeutic benefit in these patients by enhancing ICI effectiveness."<a href="https://www.cell.com/cancer-cell/fulltext/S1535-6108(23)00321-5" rel="nofollow noopener" translate="no" target="_blank">https://www.cell.com/cancer-cell/fulltext/S1535-6108(23)00321-5</a>

Alan KotokA biotechnology company designing immunotherapies for solid tumor cancers with a patient's white blood cells is raising $80 million in its initial public offering or IPO. <a href="https://sciencebusiness.technewslit.com/?p=45015" rel="nofollow noopener" target="_blank">https://sciencebusiness.technewslit.com/?p=45015</a> <a href="https://journa.host/tags/News" class="mention hashtag" rel="nofollow noopener" target="_blank">#News</a> <a href="https://journa.host/tags/Press" class="mention hashtag" rel="nofollow noopener" target="_blank">#Press</a> <a href="https://journa.host/tags/Science" class="mention hashtag" rel="nofollow noopener" target="_blank">#Science</a> <a href="https://journa.host/tags/Business" class="mention hashtag" rel="nofollow noopener" target="_blank">#Business</a> <a href="https://journa.host/tags/Biotechnology" class="mention hashtag" rel="nofollow noopener" target="_blank">#Biotechnology</a> <a href="https://journa.host/tags/Cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cancer</a> <a href="https://journa.host/tags/SolidTumor" class="mention hashtag" rel="nofollow noopener" target="_blank">#SolidTumor</a> <a href="https://journa.host/tags/Finance" class="mention hashtag" rel="nofollow noopener" target="_blank">#Finance</a> <a href="https://journa.host/tags/Immunotherapy" class="mention hashtag" rel="nofollow noopener" target="_blank">#Immunotherapy</a> TCells <a href="https://journa.host/tags/ClinicalTrial" class="mention hashtag" rel="nofollow noopener" target="_blank">#ClinicalTrial</a> <a href="https://journa.host/tags/Lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#Lymphocytes</a> <a href="https://journa.host/tags/Investment" class="mention hashtag" rel="nofollow noopener" target="_blank">#Investment</a> <a href="https://journa.host/tags/IPO" class="mention hashtag" rel="nofollow noopener" target="_blank">#IPO</a> <a href="https://journa.host/tags/ImmuneSystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#ImmuneSystem</a> <a href="https://journa.host/tags/Licensing" class="mention hashtag" rel="nofollow noopener" target="_blank">#Licensing</a> <a href="https://journa.host/tags/VentureCapital" class="mention hashtag" rel="nofollow noopener" target="_blank">#VentureCapital</a>

LaurelLenzA pore-forming protein promotes <a href="https://me.dm/tags/endosome" class="mention hashtag" rel="nofollow noopener" target="_blank">#endosome</a> leakiness in <a href="https://me.dm/tags/dendriticcells" class="mention hashtag" rel="nofollow noopener" target="_blank">#dendriticcells</a> (DC). This helps explain how these specialized <a href="https://me.dm/tags/immune" class="mention hashtag" rel="nofollow noopener" target="_blank">#immune</a> cells can capture and present <a href="https://me.dm/tags/antigen" class="mention hashtag" rel="nofollow noopener" target="_blank">#antigen</a> to regulate activation of T <a href="https://me.dm/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a>. <a href="https://me.dm/tags/crosspresentation" class="mention hashtag" rel="nofollow noopener" target="_blank">#crosspresentation</a> <a href="https://me.dm/tags/crosspriming" class="mention hashtag" rel="nofollow noopener" target="_blank">#crosspriming</a> <a href="https://me.dm/tags/antigenpresentation" class="mention hashtag" rel="nofollow noopener" target="_blank">#antigenpresentation</a> <a href="https://me.dm/tags/phagocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#phagocytes</a><a href="https://www.science.org/doi/10.1126/science.adg8802" rel="nofollow noopener" target="_blank">https://www.science.org/doi/10.1126/science.adg8802</a>

Khurram Wadee ✅<a href="https://mastodon.org.uk/tags/xkcd" class="mention hashtag" rel="nofollow noopener" target="_blank">#xkcd</a>: <a href="https://mastodon.org.uk/tags/Lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#Lymphocytes</a><a href="https://xkcd.com/2749/" rel="nofollow noopener" target="_blank">https://xkcd.com/2749/</a>

Arjan BoltjesRecent work from University of Basel in Nature Communications looking into <a href="https://mastodon.social/tags/Tcell" class="mention hashtag" rel="nofollow noopener" target="_blank">#Tcell</a> <a href="https://mastodon.social/tags/exhaustion" class="mention hashtag" rel="nofollow noopener" target="_blank">#exhaustion</a>, indicating a role for the SNX9 <a href="https://mastodon.social/tags/gene" class="mention hashtag" rel="nofollow noopener" target="_blank">#gene</a>. Knocking out this gene led to phenotypical and functional changes, e.g. Tmem differentiation, IFNg production, reduced <a href="https://mastodon.social/tags/tumour" class="mention hashtag" rel="nofollow noopener" target="_blank">#tumour</a> growth, and improved survival in certain models.<a href="https://www.nature.com/articles/s41467-022-35583-w" rel="nofollow noopener" target="_blank">https://www.nature.com/articles/s41467-022-35583-w</a><a href="https://mastodon.social/tags/Tcells" class="mention hashtag" rel="nofollow noopener" target="_blank">#Tcells</a> <a href="https://mastodon.social/tags/Cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cancer</a> <a href="https://mastodon.social/tags/Immunology" class="mention hashtag" rel="nofollow noopener" target="_blank">#Immunology</a> <a href="https://mastodon.social/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a> <a href="https://mastodon.social/tags/CancerImmunology" class="mention hashtag" rel="nofollow noopener" target="_blank">#CancerImmunology</a> <a href="https://mastodon.social/tags/SingleCell" class="mention hashtag" rel="nofollow noopener" target="_blank">#SingleCell</a> <a href="https://mastodon.social/tags/scRNAseq" class="mention hashtag" rel="nofollow noopener" target="_blank">#scRNAseq</a> <a href="https://mastodon.social/tags/RNAseq" class="mention hashtag" rel="nofollow noopener" target="_blank">#RNAseq</a>Found via <a href="https://mastodon.social/@sflorg" class="u-url mention" rel="nofollow noopener" target="_blank">@sflorg</a>

Scientific FrontlineA research group at the University of Basel has identified a <a href="https://mastodon.social/tags/gene" class="mention hashtag" rel="nofollow noopener" target="_blank">#gene</a> that drives T <a href="https://mastodon.social/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a> (<a href="https://mastodon.social/tags/Tcell" class="mention hashtag" rel="nofollow noopener" target="_blank">#Tcell</a>) to exhaustion. This finding opens up new approaches for more effective <a href="https://mastodon.social/tags/immunotherapies" class="mention hashtag" rel="nofollow noopener" target="_blank">#immunotherapies</a>. <a href="https://mastodon.social/tags/Biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#Biology</a> <a href="https://mastodon.social/tags/Medical" class="mention hashtag" rel="nofollow noopener" target="_blank">#Medical</a> <a href="https://mastodon.social/tags/sflorg" class="mention hashtag" rel="nofollow noopener" target="_blank">#sflorg</a> <a href="https://www.sflorg.com/2023/02/bio02022301.html" rel="nofollow noopener" target="_blank">https://www.sflorg.com/2023/02/bio02022301.html</a>

Lorraine<a href="https://nitter.pussthecat.org/tactnowinfo/status/1611185494326497282?s=46" rel="nofollow noopener" target="_blank">https://nitter.pussthecat.org/tactnowinfo/status/1611185494326497282?s=46</a> <a href="https://zeroes.ca/tags/virus" class="mention hashtag" rel="nofollow noopener" target="_blank">#virus</a> <a href="https://zeroes.ca/tags/fungi" class="mention hashtag" rel="nofollow noopener" target="_blank">#fungi</a> <a href="https://zeroes.ca/tags/bacteria" class="mention hashtag" rel="nofollow noopener" target="_blank">#bacteria</a> <a href="https://zeroes.ca/tags/tcells" class="mention hashtag" rel="nofollow noopener" target="_blank">#tcells</a> <a href="https://zeroes.ca/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a> <a href="https://zeroes.ca/tags/bcells" class="mention hashtag" rel="nofollow noopener" target="_blank">#bcells</a> <a href="https://zeroes.ca/tags/cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#cancer</a> <a href="https://zeroes.ca/tags/hiv" class="mention hashtag" rel="nofollow noopener" target="_blank">#hiv</a> <a href="https://zeroes.ca/tags/xbb15" class="mention hashtag" rel="nofollow noopener" target="_blank">#xbb15</a> Tbh I’m not sure I’d be able to convince 90% of the population that is already checked out & in complete denial..I just post for those people who are still trying & wondering if they should just give up🖤<a href="https://zeroes.ca/tags/dontGiveUp" class="mention hashtag" rel="nofollow noopener" target="_blank">#dontGiveUp</a> <a href="https://zeroes.ca/tags/DontInhaleTheVirus" class="mention hashtag" rel="nofollow noopener" target="_blank">#DontInhaleTheVirus</a> <a href="https://zeroes.ca/tags/viralDose" class="mention hashtag" rel="nofollow noopener" target="_blank">#viralDose</a> <a href="https://zeroes.ca/tags/HEPA" class="mention hashtag" rel="nofollow noopener" target="_blank">#HEPA</a> <a href="https://zeroes.ca/tags/keepMasking" class="mention hashtag" rel="nofollow noopener" target="_blank">#keepMasking</a> <a href="https://zeroes.ca/tags/CovidPapers" class="mention hashtag" rel="nofollow noopener" target="_blank">#CovidPapers</a> <a href="https://zeroes.ca/tags/LongCovid" class="mention hashtag" rel="nofollow noopener" target="_blank">#LongCovid</a>

Sandy LawrenceLinchpin of human immune system, T-lymphocytes actually come in a number of subpopulations. CD-4 cells are 'helper-inducer T-cells' that support the production of antibodies by B-lymphocytes. CD-8 cells are cytotoxic T-cells that directly kill microorganisms or cancer cells. Memory T cells are long-lived lymphocytes that can respond to foreign antigens encountered before, even over the entire lifetime of an individual. All of these cells are absolutely required to counter infections such as coronaviruses, measles + hundreds of other infectious diseases in particular. This photo is a colorized scanning electron micrograph of a T-lymphocyte. Not golden in real life but absolute gold in terms of our survival as a species. Good time of the year to give thanks. <a href="https://aus.social/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a> <a href="https://aus.social/tags/immunity" class="mention hashtag" rel="nofollow noopener" target="_blank">#immunity</a>

halama_immunoThe delicate balance between CD4 and CD8 T cells within solid tumors: a new aspect of the role of CD4 T cells in a glioblastoma model reveals possible synergies with a CD40 agonistic approach. <a href="https://mstdn.science/tags/immunology" class="mention hashtag" rel="nofollow noopener" target="_blank">#immunology</a> <a href="https://mstdn.science/tags/Oncology" class="mention hashtag" rel="nofollow noopener" target="_blank">#Oncology</a> <a href="https://mstdn.science/tags/Immunotherapy" class="mention hashtag" rel="nofollow noopener" target="_blank">#Immunotherapy</a> <a href="https://mstdn.science/tags/Lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#Lymphocytes</a> <a href="https://jitc.bmj.com/content/10/12/e005293" rel="nofollow noopener" target="_blank">https://jitc.bmj.com/content/10/12/e005293</a>

halama_immunoRegulatory T cells revisited...from the "brakes" of the immune response to master regulators: here is a fresh review on the complex role of this immune cell subpopulation <a href="https://mstdn.science/tags/immunology" class="mention hashtag" rel="nofollow noopener" target="_blank">#immunology</a> <a href="https://mstdn.science/tags/Lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#Lymphocytes</a> <a href="https://qoto.org/@cyrilpedia" class="u-url mention" rel="nofollow noopener" target="_blank">@cyrilpedia</a> <a href="https://med-mastodon.com/@gpollara" class="u-url mention" rel="nofollow noopener" target="_blank">@gpollara</a> <a href="https://med-mastodon.com/@rio_sugimura" class="u-url mention" rel="nofollow noopener" target="_blank">@rio_sugimura</a> <a href="https://academic.oup.com/cei/advance-article/doi/10.1093/cei/uxac123/6961023?searchresult=1" rel="nofollow noopener" target="_blank">https://academic.oup.com/cei/advance-article/doi/10.1093/cei/uxac123/6961023?searchresult=1</a>

Freedom"In clinical studies, lymphocyte count has been described to recover to 80% of baseline value by 3 months; however, less is known about the duration of lymphopenia in real-life clinical practice."However, fingolimod-induced lymphopenia persists in 22% of patients for at least up to 1 year after fingolimod stop."<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641093/" rel="nofollow noopener" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641093/</a><a href="https://mastodon.social/tags/Immunology" class="mention hashtag" rel="nofollow noopener" target="_blank">#Immunology</a> <a href="https://mastodon.social/tags/RepairingCovidDamage" class="mention hashtag" rel="nofollow noopener" target="_blank">#RepairingCovidDamage</a> <a href="https://mastodon.social/tags/Covid19" class="mention hashtag" rel="nofollow noopener" target="_blank">#Covid19</a> <a href="https://mastodon.social/tags/lymphopenia" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphopenia</a> <a href="https://mastodon.social/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a> <a href="https://mastodon.social/tags/epidemiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#epidemiology</a> <a href="https://mastodon.social/tags/virology" class="mention hashtag" rel="nofollow noopener" target="_blank">#virology</a> Weary. Verge of tears.

Giuseppe MichieliOgura, H., Gohda, J., Lu, X. et al. Dysfunctional <a href="https://mstdn.science/tags/Sars" class="mention hashtag" rel="nofollow noopener" target="_blank">#Sars</a>-CoV-2-M protein-specific <a href="https://mstdn.science/tags/cytotoxic" class="mention hashtag" rel="nofollow noopener" target="_blank">#cytotoxic</a> T <a href="https://mstdn.science/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a> in patients recovering from severe <a href="https://mstdn.science/tags/COVID19" class="mention hashtag" rel="nofollow noopener" target="_blank">#COVID19</a>. Nat Commun 13, 7063 (2022). <a href="https://doi.org/10.1038/s41467-022-34655-1" rel="nofollow noopener" target="_blank">https://doi.org/10.1038/s41467-022-34655-1</a>

Maria SoaresJust arrived here. Still not sure how this works though.. <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#science</a> <a href="https://mastodon.social/tags/immunology" class="mention hashtag" rel="nofollow noopener" target="_blank">#immunology</a> <a href="https://mastodon.social/tags/HSCT" class="mention hashtag" rel="nofollow noopener" target="_blank">#HSCT</a> <a href="https://mastodon.social/tags/treg" class="mention hashtag" rel="nofollow noopener" target="_blank">#treg</a> <a href="https://mastodon.social/tags/lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#lymphocytes</a> <a href="https://mastodon.social/tags/celltherapies" class="mention hashtag" rel="nofollow noopener" target="_blank">#celltherapies</a> <a href="https://mastodon.social/tags/immunemodulation" class="mention hashtag" rel="nofollow noopener" target="_blank">#immunemodulation</a> <a href="https://mastodon.social/tags/CMV" class="mention hashtag" rel="nofollow noopener" target="_blank">#CMV</a> <a href="https://mastodon.social/tags/GVHD" class="mention hashtag" rel="nofollow noopener" target="_blank">#GVHD</a> will all these <a href="https://mastodon.social/tags/s" class="mention hashtag" rel="nofollow noopener" target="_blank">#s</a> help me to get content I'm keen on?

halama_immunoTumor-infiltrating lymphocytes are key players in the tumor <a href="https://mstdn.science/tags/microenvironment" class="mention hashtag" rel="nofollow noopener" target="_blank">#microenvironment</a> and for <a href="https://mstdn.science/tags/Immunotherapy" class="mention hashtag" rel="nofollow noopener" target="_blank">#Immunotherapy</a> ...but how do we bring these <a href="https://mstdn.science/tags/Lymphocytes" class="mention hashtag" rel="nofollow noopener" target="_blank">#Lymphocytes</a> into it? Here are some suggestions... <a href="https://pubmed.ncbi.nlm.nih.gov/36366354/" rel="nofollow noopener" target="_blank">https://pubmed.ncbi.nlm.nih.gov/36366354/</a>

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