ohai.social

flypapers📰 "A Drosophila model for Dent disease reveals impaired ER export of Cubilin as pathogenic mechanism" <a href="https://www.biorxiv.org/content/10.1101/2025.03.05.641445v1?rss=1" rel="nofollow noopener" translate="no" target="_blank">https://www.biorxiv.org/content/10.1101/2025.03.05.641445v1?rss=1</a> <a href="https://biologists.social/tags/Drosophila" class="mention hashtag" rel="nofollow noopener" target="_blank">#Drosophila</a> <a href="https://biologists.social/tags/Golgi" class="mention hashtag" rel="nofollow noopener" target="_blank">#Golgi</a>

flypapers📰 "Huntington's disease-associated ankyrin repeat palmitoyl transferases are rate-limiting factors in lysosome formation and fusion" <a href="https://www.biorxiv.org/content/10.1101/2025.02.06.636816v1?rss=1" rel="nofollow noopener" translate="no" target="_blank">https://www.biorxiv.org/content/10.1101/2025.02.06.636816v1?rss=1</a> <a href="https://biologists.social/tags/Drosophila" class="mention hashtag" rel="nofollow noopener" target="_blank">#Drosophila</a> <a href="https://biologists.social/tags/Adult" class="mention hashtag" rel="nofollow noopener" target="_blank">#Adult</a> <a href="https://biologists.social/tags/Golgi" class="mention hashtag" rel="nofollow noopener" target="_blank">#Golgi</a> <a href="https://biologists.social/tags/Larva" class="mention hashtag" rel="nofollow noopener" target="_blank">#Larva</a>

DJ BonsaiDer Google-Apparat. Is‘ klar.<a href="https://bildung.social/tags/Golgi" class="mention hashtag" rel="nofollow noopener" target="_blank">#Golgi</a> <a href="https://bildung.social/tags/Biologie" class="mention hashtag" rel="nofollow noopener" target="_blank">#Biologie</a> <a href="https://bildung.social/tags/korrekturentr%C3%B6t" class="mention hashtag" rel="nofollow noopener" target="_blank">#korrekturentröt</a> <a href="https://bildung.social/tags/herrje" class="mention hashtag" rel="nofollow noopener" target="_blank">#herrje</a> <a href="https://bildung.social/tags/FediLZ" class="mention hashtag" rel="nofollow noopener" target="_blank">#FediLZ</a>

eLifeA receptor protein called TGN46 has an important role in sorting secretory proteins into vesicles going to different destinations inside cells. <a href="https://fediscience.org/tags/Golgi" class="mention hashtag" rel="nofollow noopener" target="_blank">#Golgi</a> <a href="https://elifesciences.org/articles/93490?utm_source=mastodon&utm_medium=social&utm_campaign=organic_insights" rel="nofollow noopener" target="_blank">https://elifesciences.org/articles/93490?utm_source=mastodon&utm_medium=social&utm_campaign=organic_insights</a>

Stephen RoyleWow multiplexed super-res imaging. 9 different proteins mapped in one cell! This looks cool from Bewersdorf lab.<a href="https://www.biorxiv.org/content/10.1101/2023.05.17.541061v1" rel="nofollow noopener" target="_blank">https://www.biorxiv.org/content/10.1101/2023.05.17.541061v1</a><a href="https://mastodon.social/tags/cellBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#cellBiology</a> <a href="https://mastodon.social/tags/Microscopy" class="mention hashtag" rel="nofollow noopener" target="_blank">#Microscopy</a> <a href="https://mastodon.social/tags/golgi" class="mention hashtag" rel="nofollow noopener" target="_blank">#golgi</a>

David StephensFour good things happened at work today. Almost unheard of. Two great bits of new data. <a href="https://mastodon.social/tags/cilia" class="mention hashtag" rel="nofollow noopener" target="_blank">#cilia</a> <a href="https://mastodon.social/tags/Golgi" class="mention hashtag" rel="nofollow noopener" target="_blank">#Golgi</a> <a href="https://mastodon.social/tags/ExtracellularMatrix" class="mention hashtag" rel="nofollow noopener" target="_blank">#ExtracellularMatrix</a> One modified piece of equipment that means we can do some cool new experiments. And I got some code to run a mathematical model given to us by a collaborator. New software. Step learning curve. Worth remembering days like these. They do still happen!

Biology OpenNicola L. Stevenson et al. complete a future leader <a href="https://mstdn.science/tags/review" class="mention hashtag" rel="nofollow noopener" target="_blank">#review</a> of the well-studied interactions between the <a href="https://mstdn.science/tags/Golgi" class="mention hashtag" rel="nofollow noopener" target="_blank">#Golgi</a>, <a href="https://mstdn.science/tags/cilium" class="mention hashtag" rel="nofollow noopener" target="_blank">#cilium</a> and <a href="https://mstdn.science/tags/extra" class="mention hashtag" rel="nofollow noopener" target="_blank">#extra</a> cellular matrix, with a particular focus on how the interplay between all three compartments underpins healthy tissue. <a href="https://journals.biologists.com/bio/article/12/2/bio059719/287059/The-factory-the-antenna-and-the-scaffold-the-three#Biology" rel="nofollow noopener" target="_blank">https://journals.biologists.com/bio/article/12/2/bio059719/287059/The-factory-the-antenna-and-the-scaffold-the-three#Biology</a> <a href="https://mstdn.science/tags/Science" class="mention hashtag" rel="nofollow noopener" target="_blank">#Science</a> <a href="https://mstdn.science/tags/BiologyOpen" class="mention hashtag" rel="nofollow noopener" target="_blank">#BiologyOpen</a> <a href="https://mstdn.science/tags/AcademicMastodon" class="mention hashtag" rel="nofollow noopener" target="_blank">#AcademicMastodon</a>

David StephensGreat review from Nicola Stevenson. Part of our team in Biochemistry at the U of Bristol researching <a href="https://mastodon.social/tags/Golgi" class="mention hashtag" rel="nofollow noopener" target="_blank">#Golgi</a> <a href="https://mastodon.social/tags/cilia" class="mention hashtag" rel="nofollow noopener" target="_blank">#cilia</a> and <a href="https://mastodon.social/tags/extracellularmatrix" class="mention hashtag" rel="nofollow noopener" target="_blank">#extracellularmatrix</a> <a href="https://journals.biologists.com/bio/article/12/2/bio059719/287059/The-factory-the-antenna-and-the-scaffold-the-three" rel="nofollow noopener" target="_blank">https://journals.biologists.com/bio/article/12/2/bio059719/287059/The-factory-the-antenna-and-the-scaffold-the-three</a>Part of Biology Open's series of Future Leader Reviews. <a href="https://mstdn.science/@BiologyOpen" class="u-url mention" rel="nofollow noopener" target="_blank">@BiologyOpen</a>Nikki is making great progress on our @BBSRC sLoLa. This review includes some thoughts beyond her current work towards more integration with cilia biology.

The EMBO JournalCover feature in issue 42/2:<a href="https://sciencemastodon.com/tags/Golgi" class="mention hashtag" rel="nofollow noopener" target="_blank">#Golgi</a> <a href="https://sciencemastodon.com/tags/oxygen" class="mention hashtag" rel="nofollow noopener" target="_blank">#oxygen</a> sensor controlling <a href="https://sciencemastodon.com/tags/intestinal" class="mention hashtag" rel="nofollow noopener" target="_blank">#intestinal</a> ‘mucin <a href="https://sciencemastodon.com/tags/glycosylation" class="mention hashtag" rel="nofollow noopener" target="_blank">#glycosylation</a> by Tal Ilani, Deborah Fass and colleagues with SciStories.comAnd: Gut colonization via <a href="https://sciencemastodon.com/tags/GTPase" class="mention hashtag" rel="nofollow noopener" target="_blank">#GTPase</a>-less EF-G paralog <a href="https://sciencemastodon.com/tags/Yeast" class="mention hashtag" rel="nofollow noopener" target="_blank">#Yeast</a> cells in two minds about <a href="https://sciencemastodon.com/tags/cellcycle" class="mention hashtag" rel="nofollow noopener" target="_blank">#cellcycle</a> start <a href="https://sciencemastodon.com/tags/MASTL" class="mention hashtag" rel="nofollow noopener" target="_blank">#MASTL</a>/#PP2A module restraining <a href="https://sciencemastodon.com/tags/PI3K" class="mention hashtag" rel="nofollow noopener" target="_blank">#PI3K</a>-Akt Zinc-dependent structural transition in ALS-mutated <a href="https://sciencemastodon.com/tags/SOD1" class="mention hashtag" rel="nofollow noopener" target="_blank">#SOD1</a> <a href="https://www.embopress.org/toc/14602075/2023/42/2" rel="nofollow noopener" target="_blank">https://www.embopress.org/toc/14602075/2023/42/2</a>

Luc Reym⌬ndTo the <a href="https://mstdn.science/tags/golgi" class="mention hashtag" rel="nofollow noopener" target="_blank">#golgi</a> lovers out there, especially <a href="https://mstdn.science/@fran_bottanelli" class="u-url mention" rel="nofollow noopener" target="_blank">@fran_bottanelli</a> !golgi or not golgi? these are HeLa cells imaged by widefield. a single plane more or less through the nucleus (based on DNA signal)What would be the best FP-fusion for colocalization? any suggestion welcome!

Biology OpenIn this Research Article, Levente Kovacs, Agnieszka Fatalska and David Glover present a new method to relocalise <a href="https://mstdn.science/tags/golgi" class="mention hashtag" rel="nofollow noopener" target="_blank">#golgi</a> or <a href="https://mstdn.science/tags/centrosome" class="mention hashtag" rel="nofollow noopener" target="_blank">#centrosome</a> proteins to the <a href="https://mstdn.science/tags/mitochondria" class="mention hashtag" rel="nofollow noopener" target="_blank">#mitochondria</a> in Drosophila cells. Applying this technique to Drosophila <a href="https://mstdn.science/tags/Sas6" class="mention hashtag" rel="nofollow noopener" target="_blank">#Sas6</a> reveals its high affinity for <a href="https://mstdn.science/tags/Gorab" class="mention hashtag" rel="nofollow noopener" target="_blank">#Gorab</a>: <a href="https://journals.biologists.com/bio/article/11/11/bio059545/283148/Targeting-Drosophila-Sas6-to-mitochondria-reveals" rel="nofollow noopener" target="_blank">https://journals.biologists.com/bio/article/11/11/bio059545/283148/Targeting-Drosophila-Sas6-to-mitochondria-reveals</a> <a href="https://mstdn.science/tags/CellScience" class="mention hashtag" rel="nofollow noopener" target="_blank">#CellScience</a> <a href="https://mstdn.science/tags/Centriole" class="mention hashtag" rel="nofollow noopener" target="_blank">#Centriole</a> <a href="https://mstdn.science/tags/Biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#Biology</a> <a href="https://mstdn.science/tags/Science" class="mention hashtag" rel="nofollow noopener" target="_blank">#Science</a> <a href="https://mstdn.science/tags/AcademicMastodon" class="mention hashtag" rel="nofollow noopener" target="_blank">#AcademicMastodon</a> <a href="https://mstdn.science/tags/Drosophila" class="mention hashtag" rel="nofollow noopener" target="_blank">#Drosophila</a>

MzeeCellular Landcape<a href="https://gaelmcgill.artstation.com/projects/Pm0JL1" rel="nofollow noopener" target="_blank">https://gaelmcgill.artstation.com/projects/Pm0JL1</a> <a href="https://www.cellsignal.com/pathways/cellular-landscapes" rel="nofollow noopener" target="_blank">https://www.cellsignal.com/pathways/cellular-landscapes</a>Cell Signaling Technology<a href="https://www.digizyme.com/cst_landscapes.html" rel="nofollow noopener" target="_blank">https://www.digizyme.com/cst_landscapes.html</a> <a href="https://universeodon.com/tags/cell" class="mention hashtag" rel="nofollow noopener" target="_blank">#cell</a> signaling <a href="https://universeodon.com/tags/eukaryote" class="mention hashtag" rel="nofollow noopener" target="_blank">#eukaryote</a> <a href="https://universeodon.com/tags/mitochondria" class="mention hashtag" rel="nofollow noopener" target="_blank">#mitochondria</a> <a href="https://universeodon.com/tags/transcription" class="mention hashtag" rel="nofollow noopener" target="_blank">#transcription</a> <a href="https://universeodon.com/tags/Golgi" class="mention hashtag" rel="nofollow noopener" target="_blank">#Golgi</a> <a href="https://universeodon.com/tags/cytoskeleton" class="mention hashtag" rel="nofollow noopener" target="_blank">#cytoskeleton</a> <a href="https://universeodon.com/tags/adhesion" class="mention hashtag" rel="nofollow noopener" target="_blank">#adhesion</a> <a href="https://universeodon.com/tags/protein" class="mention hashtag" rel="nofollow noopener" target="_blank">#protein</a> synthesis

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