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Mastodon: AboutGet the appKeyboard shortcutsView source codev4.4.0-nightly.2025-04-01

#dendrites

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katch wreck

`In this work, we investigated the #dendrites of layer 2 and 3 (L2/3) pyramidal #neurons of the human cerebral cortex ex vivo. In these neurons, we discovered a class of #calcium-mediated dendritic action potentials (dCaAPs) whose waveform and effects on #neuronal output have not been previously described. In contrast to typical all-or-none action potentials, dCaAPs were graded; their amplitudes were maximal for threshold-level stimuli but dampened for stronger stimuli`

science.org/doi/10.1126/scienc

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Scientific Frontline

#Nerve #cells (#neurons ) are amongst the most complex cell types in our body. They achieve this complexity during development by extending ramified branches called #dendrites and #axons and establishing thousands of synapses to form intricate networks.
#Neuroscience #sflorg
sflorg.com/2024/04/ns04082401.

www.sflorg.comFueling nerve cell function and plasticityHow mitochondria control tissue rejuvenation and synaptic plasticity in the adult mouse brain
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katch wreck

`In contrast to typical all-or-none action potentials, dCaAPs were graded; their amplitudes were maximal for threshold-level stimuli but dampened for stronger stimuli. These dCaAPs enabled the #dendrites of individual human neocortical pyramidal #neurons to classify linearly nonseparable inputs—a computation conventionally thought to require multilayered #networks.`

science.org/doi/10.1126/scienc

hat tip @ScienceScholar

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katch wreck

"Here we combine cable and renewal theory to describe how input fluctuations shape the response of neuronal ensembles with active #dendrites. We found that dendritic input readily and potently controls interspike interval dispersion. This phenomenon can be understood by considering that #neurons display three fundamental operating regimes: one mean-driven regime and two fluctuation-driven regimes."

nature.com/articles/s43588-023

NatureDendritic excitability controls overdispersion - Nature Computational ScienceA mathematical framework that allows computing the input–output function of neurons with active dendrites reveals how dendrites readily and potently control the response variability, a result that is experimentally confirmed.
Continued thread
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CelloMom On Cars

Dendrite formation is the bane of lithium batteries.

"In the new research, Li and his team stop #dendrites from forming by using micron-sized silicon particles in the anode to constrict the lithiation reaction and facilitate homogeneous plating of a thick layer of #lithium metal."

#batteries
pv-magazine.com/2024/01/15/new

pv magazine InternationalNew solid state battery charges in minutes, lasts for thousands of cyclesResearchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a new lithium metal battery that can be charged and discharged at least 6,000 times — more than any other pouch battery cell — and can be recharged in a matter of minutes.
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Toyooka Lab

Our lab (Toyooka Lab @LabToyooka) at Drexel University in Philadelphia is seeking a research assistant who is enthusiastic about autism research. We study the efficacy of peptides on neuronal morphology (neurite/spine/synapse formation), neural circuits and behaviors using autism mouse models (See the details about the project at the lab webpage: toyooka-lab.academic.ws/).

Please see the details and apply for this position (Job #: 501807) at the Drexel Human Resources website. careers.drexel.edu/en-us/job/5

If you have any questions, please email me at kt469@drexel.edu.
#autism #ASD #therapy #DrugDiscovery #ResearchAssistant #ResearchAssistantJob #AcademicJob #LabTechnician #neuroscience #brain #CellBiology #BrainDevelopment #neurodevelopment #neurodevelopmentalDisorder #Axon #dendrites #Synapse #NeuralCircuit #philadelphia

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RashaKamel

"An international research team involving scientists has described the process of growing three-dimensional manganese dendrites. The researchers found that it occurs through accretion of manganese oxide nanoparticles. Understanding the dynamics of the growth of three-dimensional mineral dendrites is important for various fields of science - physics, geology, material sciences and even the study of extraterrestrial environments". 
#menirals #dendrites #materialscience
eurekalert.org/news-releases/9

EurekAlert!Unravelling the hidden growth of mineral dendritesAn international research team involving scientists from the University of Vienna, the Faculty of Physics of the University of Warsaw and Univeristy of Edinburgh has described the process of growing three-dimensional manganese dendrites. The researchers found that it occurs through accretion of manganese oxide nanoparticles. Understanding the dynamics of the growth of three-dimensional mineral dendrites is important for various fields of science - physics, geology, material sciences and even the study of extraterrestrial environments. Not only are scientists gaining valuable insights into the history of rocks and minerals, the knowledge can also be used in industry, for example in the production of synthetic materials with new properties.
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Hobson Lane

Yiota Poirazi's (nitter.net/yiotapoirazi) microbiology lab in Greece is coming up with some really intriguing neuroscience concepts that might improve deep learning artificial neutral networks:
- #engrams :: subgraphs of neurons for encoding memories
- #dendrites :: appear to have the computational capacity of a multilayer deep learning neural network

Python framework `dendrify` used to add dendrite computational models to #DeepLearning #NeuralNetworks.

#Brain Inspired: pca.st/episode/dd89b13f-c296-4

NitterYiota Poirazi (@YiotaPoirazi)Computational (mostly) Neuroscientist. I'm interested in understanding how dendrites contribute to brain functions.
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