PLOS Biology<p>Nuclear localization of <a href="https://fediscience.org/tags/TDP43" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>TDP43</span></a> is crucial for its function during <a href="https://fediscience.org/tags/RNAprocessing" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>RNAprocessing</span></a> & <a href="https://fediscience.org/tags/neurodegeneration" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neurodegeneration</span></a>. @AyalaLab1 &co show that <a href="https://fediscience.org/tags/RNAbinding" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>RNAbinding</span></a> & macromolecular assembly, including via <a href="https://fediscience.org/tags/LLPS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>LLPS</span></a>, play a central role in TDP-43 nuclear retention <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PLOSBiology</span></a> <a href="https://plos.io/3v372fT" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3v372fT</span><span class="invisible"></span></a></p>
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PLOS Biology<p>This Primer explores a <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PLOSBiology</span></a> study which shows that 2 known congenital <a href="https://fediscience.org/tags/hydrocephalus" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hydrocephalus</span></a> Trim71 mutations lead to distinct ectopic <a href="https://fediscience.org/tags/RNAbinding" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>RNAbinding</span></a> that influences <a href="https://fediscience.org/tags/neurogenesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neurogenesis</span></a> in vitro & may contribute to pathology. Primer: <a href="https://plos.io/3xd98Y4" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3xd98Y4</span><span class="invisible"></span></a> Paper: <a href="https://plos.io/3IbzKz4" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3IbzKz4</span><span class="invisible"></span></a></p>
PLOS Biology<p>This Primer explores a <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PLOSBiology</span></a> study which shows that 2 known congenital <a href="https://fediscience.org/tags/hydrocephalus" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hydrocephalus</span></a> Trim71 mutations lead to distinct ectopic <a href="https://fediscience.org/tags/RNAbinding" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>RNAbinding</span></a> that influences <a href="https://fediscience.org/tags/neurogenesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neurogenesis</span></a> in vitro & may contribute to pathology. Primer: <a href="https://plos.io/3xd98Y4" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3xd98Y4</span><span class="invisible"></span></a> Paper: <a href="https://plos.io/3IbzKz4" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3IbzKz4</span><span class="invisible"></span></a></p>
PLOS Biology<p>This Primer explores a <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PLOSBiology</span></a> study which shows that 2 known congenital <a href="https://fediscience.org/tags/hydrocephalus" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hydrocephalus</span></a> Trim71 mutations lead to distinct ectopic <a href="https://fediscience.org/tags/RNAbinding" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>RNAbinding</span></a> that influences <a href="https://fediscience.org/tags/neurogenesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neurogenesis</span></a> in vitro & may contribute to pathology. Primer: <a href="https://plos.io/3xd98Y4" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3xd98Y4</span><span class="invisible"></span></a> Paper: <a href="https://plos.io/3IbzKz4" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3IbzKz4</span><span class="invisible"></span></a></p>
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